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Article

G-308A TNF-alpha polymorphism is associated with an increased risk of invasive cervical cancer.

Biochemical and biophysical research communications - 26 Aug 2005

Duarte Isabel, Santos Alexandra, Sousa Hugo, Catarino Raquel, Pinto Daniela, Matos Ana, Pereira Deolinda, Moutinho José, Canedo Paulo, Machado José Carlos, Medeiros Rui

Abstract excerpt

Cervical cancer is initiated by high-risk human papillomaviruses (HPV-16 and HPV-18), but an effective immune response may control the progression of this disease. Tumor necrosis factor-alpha (TNF-alpha) is a pro-inflammatory cytokine, that has been implicated in several cancers. In a case-control study, we evaluated the association between the G-308A TNF-alpha promoter polymorphism and the risk for invasive...

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PMID: 16009345
DOI: 10.1016/j.bbrc.2005.06.137

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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