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Article

Allelic variants and immunostaining profile in CXCL12/CXCR4 axis: An investigation of association with prognosis in prostate cancer.

Pathology, research and practice - 1 Oct 2023

Francelino Amanda Letícia, Pereira Érica Romão, Pinheiro Laís Capelasso Lucas, Soares Adrielli Caroline, Mendonça Ana Carla, Fuganti Paulo Emílio, Frantine-Silva Wilson, de Oliveira Karen Brajão, Serpeloni Juliana Mara, Guembarovski Roberta Losi

Abstract excerpt

Prostate cancer (PCa) is the malignant neoplasm that most commonly affects men and is an important cause of death. It can be detected by changes in serum levels of Prostate Specific Antigen (PSA) and digital rectal examination, but often symptoms do not appear until advanced stages and metastases. The C-X-C Motif Chemokine Ligand 12/C-X-C Motif Chemokine Receptor 4 (CXCL12/CXCR4) axis acts in cell migration and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 37738928
DOI: 10.1016/j.prp.2023.154806

Genes

CXCR4
CXCL12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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