Article
Discovery of novel secreted virulence factors from Salmonella enterica serovar Typhimurium by proteomic analysis of culture supernatants.
Infection and immunity - 1 Jan 2011
Niemann George S, Brown Roslyn N, Gustin Jean K, Stufkens Afke, Shaikh-Kidwai Afshan S, Li Jie, McDermott Jason E, Brewer Heather M, Schepmoes Athena, Smith Richard D, Adkins Joshua N, Heffron Fred
Abstract excerpt
Salmonella enterica serovar Typhimurium is a leading cause of acute gastroenteritis throughout the world. This pathogen has two type III secretion systems (TTSS) encoded in Salmonella pathogenicity islands 1 and 2 (SPI-1 and SPI-2) that deliver virulence factors (effectors) to the host cell cytoplasm and are required for virulence. While many effectors have been identified and at least partially characterized,...
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