Article
Essential role of Salmonella Enteritidis DNA adenine methylase in modulating inflammasome activation.
BMC microbiology - 28 Jul 2020
Guo Yaxin, Gu Dan, Huang Tingting, Cao Liyan, Zhu Xinyu, Zhou Yi, Wang Kangru, Kang Xilong, Meng Chuang, Jiao Xinan, Pan Zhiming
Abstract excerpt
BACKGROUND: Salmonella Enteritidis (SE) is one of the major foodborne zoonotic pathogens of worldwide importance which can induce activation of NLRC4 and NLRP3 inflammasomes during infection. Given that the inflammasomes play an essential role in resisting bacterial infection, Salmonella has evolved various strategies to regulate activation of the inflammasome, most of which largely remain unclear. RESULTS: A...
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