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Independent evolution of functionally exchangeable mitochondrial outer membrane import complexes

20 Jun 2018

Abstract excerpt

Assembly and/or insertion of a subset of mitochondrial outer membrane (MOM) proteins, including subunits of the main MOM translocase, require the fungi-specific Mim1/Mim2 complex. So far it was unclear which proteins accomplish this task in other eukaryotes. Here, we show by reciprocal complementation that the MOM protein pATOM36 of trypanosomes is a functional analogue of yeast Mim1/Mim2 complex, even though...

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PMID: 29923829
DOI: 10.7554/elife.34488

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