Article
The Importance of Sex Stratification in Autoimmune Disease Biomarker Research: A Systematic Review.
Frontiers in immunology - 1 Jan 2018
Purnamawati Kristy, Ong Jamie Ann-Hui, Deshpande Siddharth, Tan Warren Kok-Yong, Masurkar Nihar, Low Jackson Kwee, Drum Chester Lee
Abstract excerpt
The immune system is highly dynamic and regulated by many baseline characteristic factors. As such, significant variability may exist among different patient groups suffering from the same autoimmune disease (AD). However, contemporary research practices tend to take the reductionist aggregate approach: they do not segment AD patients before embarking on biomarker discovery. This approach has been productive:...
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