Article
Genetics of common forms of heart failure: challenges and potential solutions.
Current opinion in cardiology - 1 May 2015
Rau Christoph D, Lusis Aldons J, Wang Yibin
Abstract excerpt
PURPOSE OF REVIEW: In contrast to many other human diseases, the use of genome-wide association studies (GWAS) to identify genes for heart failure (HF) has had limited success. We will discuss the underlying challenges as well as potential new approaches to understanding the genetics of common forms of HF. RECENT FINDINGS: Recent research using intermediate phenotypes, more detailed and quantitative...
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