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Article

APOE ε4 status in healthy older African Americans is associated with deficits in pattern separation and hippocampal hyperactivation.

Neurobiology of aging - 1 Sept 2018

Sinha Neha, Berg Chelsie N, Tustison Nicholas J, Shaw Ashlee, Hill Diane, Yassa Michael A, Gluck Mark A

Abstract excerpt

African Americans are 1.4 times more likely than European Americans to carry the apolipoprotein E (APOE) ε4 allele, a risk factor for Alzheimer's disease (AD). However, little is known about the neural correlates of cognitive function in older African Americans and how they relate to genetic risk for AD. In particular, no past study on African Americans has examined the effect of APOE ε4 status on pattern...

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Identifiers

PMID: 29909179
DOI: 10.1016/j.neurobiolaging.2018.05.023
PMCID: PMC6392014

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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