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Article

Spatial pattern separation differences in older adult carriers and non-carriers for the apolipoprotein E epsilon 4 allele.

Neurobiology of learning and memory - 1 Mar 2016

Sheppard David P, Graves Lisa V, Holden Heather M, Delano-Wood Lisa, Bondi Mark W, Gilbert Paul E

Abstract excerpt

We examined the performance of healthy young (n=57) and older adults (n=43) genotyped as apolipoprotein E-ε4 (APOE-ε4) carriers or APOE-ε4 non-carriers on a delayed match-to-sample task involving varying degrees of spatial interference hypothesized to assess spatial pattern separation. Older adult ε4 carriers were further divided into "impaired" and "unimpaired" groups based on their performance on a standardized...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25957133
DOI: 10.1016/j.nlm.2015.04.011
PMCID: PMC4635106

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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