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Article

Deletion of DDB1- and CUL4- associated factor-17 (Dcaf17) gene causes spermatogenesis defects and male infertility in mice

11 Jun 2018

Abstract excerpt

Abstract DDB1– and CUL4–associated factor 17 ( Dcaf17 ) is a member of DCAF family genes that encode substrate receptor proteins for Cullin-RING E3 ubiquitin ligases, which play critical roles in many cellular processes. To unravel the function of DCAF17, we performed expression profiling of Dcaf17 in different tissues of wild type mouse by qRT-PCR and generated Dcaf17 knockout mice by gene targeting. Expression...

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Identifiers

PMID: 29907856
DOI: 10.1038/s41598-018-27379-0

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