Article
Insights intoCampylobacter jejunicolonization of the mammalian intestinal tract using a novel mouse model of infection
4 Mar 2015
Abstract excerpt
A lack of relevant disease models for Campylobacter jejuni has long been an obstacle to research into this common enteric pathogen. We recently published that mice deficient in Single IgG Interleukin-1 related receptor (SIGIRR), a repressor of MyD88-dependent innate immune signaling, were highly susceptible to enteric infection by murine bacterial pathogens. Subsequently, we successfully employed these mice as an...
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