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Article

Stratification of candidate genes for Parkinson's disease using weighted protein-protein interaction network analysis.

BMC genomics - 13 Jun 2018

Ferrari Raffaele, Kia Demis A, Tomkins James E, Hardy John, Wood Nicholas W, Lovering Ruth C, Lewis Patrick A, Manzoni Claudia

Abstract excerpt

BACKGROUND: Genome wide association studies (GWAS) have helped identify large numbers of genetic loci that significantly associate with increased risk of developing diseases. However, translating genetic knowledge into understanding of the molecular mechanisms underpinning disease (i.e. disease-specific impacted biological processes) has to date proved to be a major challenge. This is primarily due to...

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Identifiers

PMID: 29898659
DOI: 10.1186/s12864-018-4804-9
PMCID: PMC6000968

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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