Article
[Associations of SUMO4 polymorphisms with tacrolimus concentrations in Chinese renal transplant recipients].
Yao xue xue bao = Acta pharmaceutica Sinica - 1 Feb 2015
Liu Xiao-Man, Li Jia-Li, Wang Hong-Yang, Fu Qian, Li Jun, Liu Shu, Sun Ping-Ping, Wang Chang-Xi, Huang Min
Abstract excerpt
The study aims to investigate the associations of SUMO4 polymorphisms with tacrolimus concentrations in Chinese renal transplant recipients. Blood samples and clinical data were collected from 132 renal transplant recipients with tacrolimus treatment. CYP3A5*3 genotypes were detected by PCR-RFLP, and SUMO4 (rs237024, rs237025) genotypes were detected by Sequenom® MassARRAY system. SUMO4 rs237024 and rs237025...
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