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Article

NHE1 is upregulated in gastric cancer and regulates gastric cancer cell proliferation, migration and invasion

18 Jan 2017

Abstract excerpt

Na+/H+ exchanger isoform 1 (NHE1) is known to play a key role in regulating intracellular pH and osmotic homeostasis and is involved in the development and progression of several types of cancer. However, the function and specific mechanism of NHE1 in gastric cancer (GC) are not clearly understood. In the present study, we report that NHE1 is overexpressed in tissues and cell lines from GC patients, and knockdown...

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PMID: 28098891
DOI: 10.3892/or.2017.5386

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