Article
Relaxation of selective constraints shapes variation of toll-like receptors in a colonial waterbird, the black-headed gull.
Immunogenetics - 1 May 2020
Podlaszczuk Patrycja, Indykiewicz Piotr, Markowski Janusz, Minias Piotr
Abstract excerpt
Nonspecific innate immune response is activated by toll-like receptors (TLRs), which recognize conserved molecular motifs characteristic for a broad spectrum of pathogens. In this study, we examined nucleotide substitution patterns and allelic diversity at five TLR genes in a wild nonpasserine bird, the black-headed gull Chroicocephalus ridibundus. We hypothesized that balancing selection can maintain high...
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