Article
Genetically driven adiposity traits increase the risk of coronary artery disease independent of blood pressure, dyslipidaemia, glycaemic traits.
European journal of human genetics : EJHG - 1 Oct 2018
Lv Wan-Qiang, Zhang Xue, Fan Kun, Xia Xin, Zhang Qiang, Liu Hui-Min, Jiang Bu-Ying, Zhang Wei-Dong, Deng Hong-Wen
Abstract excerpt
Adiposity has been associated with the risk of coronary artery disease (CAD) in observational studies, but their association may differ according to specific characteristics of studies. In Mendelian randomization (MR) analyses, genetic variants are used as instrumental variables (IVs) of exposures to examine causal effects to overcome confounding factors and reverse causation. We performed MR analyses for...
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