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Article

Assessing causal estimates of the association of obesity-related traits with coronary artery disease using a Mendelian randomization approach.

Scientific reports - 8 May 2018

Zhang Xue, Lv Wan-Qiang, Qiu Bo, Zhang Li-Jun, Qin Jian, Tang Feng-Juan, Wang Hai-Tao, Li Hua-Jie, Hao Ya-Rong

Abstract excerpt

Obesity-related traits have been associated with coronary artery disease (CAD) in observational studies, but these associations may be biased by confounding factors and reverse causation. In this study, we specifically conducted two-sample Mendelian randomization (MR) analyses to overcome these limitations and test the associations of obesity-related traits (other than body mass index (BMI)) (n = 322,154) with...

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Source

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Identifiers

PMID: 29739994
DOI: 10.1038/s41598-018-25305-y
PMCID: PMC5940685

Genes

CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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