Article
Anti-Atherogenic Effects of Vaspin on Human Aortic Smooth Muscle Cell/Macrophage Responses and Hyperlipidemic Mouse Plaque Phenotype.
International journal of molecular sciences - 11 Jun 2018
Sato Kengo, Shirai Remina, Yamaguchi Maho, Yamashita Tomoyuki, Shibata Koichiro, Okano Taisuke, Mori Yusaku, Matsuyama Taka-Aki, Ishibashi-Ueda Hatsue, Hirano Tsutomu, Watanabe Takuya
Abstract excerpt
Vaspin (visceral adipose tissue-derived serine protease inhibitor) was recently identified as a novel adipocytokine with insulin-sensitizing effects. Serum vaspin levels are reported either increased or decreased in patients with coronary artery disease. Our translational research was performed to evaluate the expression of vaspin in human coronary atherosclerotic lesions, and its effects on atherogenic responses...
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