Article
Serum vaspin concentrations are closely related to insulin resistance, and rs77060950 at SERPINA12 genetically defines distinct group with higher serum levels in Japanese population.
The Journal of clinical endocrinology and metabolism - 1 Jul 2012
Teshigawara Sanae, Wada Jun, Hida Kazuyuki, Nakatsuka Atsuko, Eguchi Jun, Murakami Kazutoshi, Kanzaki Motoko, Inoue Kentaro, Terami Takahiro, Katayama Akihiro, Iseda Izumi, Matsushita Yuichi, Miyatake Nobuyuki, McDonald John F, Hotta Kikuko, Makino Hirofumi
Abstract excerpt
CONTEXT: Vaspin is an adipokine with insulin-sensitizing effects identified from visceral adipose tissues of genetically obese rats. OBJECTIVE: We investigated genetic and nongenetic factors that define serum concentrations of vaspin. DESIGN, SETTING AND PARTICIPANTS: Vaspin levels were measured with RIA in Japanese subjects with normal fasting plasma glucose (NFG; n = 259) and type 2 diabetes patients (T2D; n =...
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