Article
Activation of the type I interferon pathway in primary Sjögren's syndrome
14 Jul 2011
Abstract excerpt
PURPOSE OF REVIEW: Recent advances suggest type I interferon (IFN) pathway as an emerging mediator of systemic autoimmunity. This review aims to summarize the latest developments in the biology of type I IFN pathway and its contributory role in the pathogenesis of autoimmune disorders with a particular focus on Sjögren's syndrome. RECENT FINDINGS: Increased circulating type I IFN levels along with upregulated...
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