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Article

Activation of the type I interferon pathway in primary Sjogren's syndrome.

Journal of autoimmunity - 1 Nov 2010

Mavragani Clio P, Crow Mary K

Abstract excerpt

Sjogren's syndrome (SS), a chronic autoimmune systemic disease affecting middle aged women, is characterized by lymphocytic infiltration of the salivary and lachrymal glands resulting in dry eyes and dry mouth. Recent advances have revealed a major role for activation of the type I interferon (IFN) pathway in the pathogenesis of the syndrome, as evidenced by the increased circulating type I IFN activity and an...

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PMID: 20674271
DOI: 10.1016/j.jaut.2010.06.012

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STAT4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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