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Genetic Variation in the H19-IGF2 Cluster Might Confer Risk of Developing Impaired Renal Function.

DNA and cell biology - 1 Jul 2018

Coto Eliecer, Díaz Corte Carmen, Tranche Salvador, Gómez Juan, Reguero Julián R, Alonso Belén, Iglesias Sara, Gil-Peña Helena, Yin Xueqian, Coto-Segura Pablo

Abstract excerpt

The H19-IGF2 imprinted gene region could be implicated in the risk of developing impaired renal function (IRF). Our aim was to determine the association of several common H19-IGF2 variants and IRF in a cohort of elderly healthy individuals. The study involved 675 individuals >65 years of age, 184 with type 2 diabetes mellitus (T2DM), and 105 with IRF (estimated glomerular filtration rate [eGFR] <60). They were...

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Identifiers

PMID: 29889555
DOI: 10.1089/dna.2017.4135

Genes

IGF2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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