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Article

Heritable rather than age-related environmental and stochastic factors dominate variation in DNA methylation of the human IGF2/H19 locus.

Human molecular genetics - 1 Mar 2007

Heijmans Bastiaan T, Kremer Dennis, Tobi Elmar W, Boomsma Dorret I, Slagboom P Eline

Abstract excerpt

Epigenetic variation may significantly contribute to the risk of common disease. Currently, little is known about the extent and causes of epigenetic variation. Here, we investigated the contribution of heritable influences and the combined effect of environmental and stochastic factors to variation in DNA methylation of the IGF2/H19 locus. Moreover, we tested whether this locus was subject to age-related...

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PMID: 17339271
DOI: 10.1093/hmg/ddm010

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IGF2

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Heritable rather than age-related environmental and stochastic factors dominate variation in DNA methylation of the human IGF2/H19 locus.PMID 17339271Read ↗

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