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Article

Rs1520220 and Rs2195239 Polymorphisms of IGF-1 Gene Associated with Histopathological Grades in IgA Nephropathy in Northwestern Chinese Han Population.

Kidney & blood pressure research - 1 Jan 2018

Wei Linting, Fu Rongguo, Liu Xinghan, Wang Li, Wang Meng, Yu Qiaoling, Tian Tian, Niu Dan, Jin Tianbo, Dai Zhijun, Gao Jie

Abstract excerpt

BACKGROUND/AIMS: Insulin-like growth factor-1 (IGF-1) plays important roles in cellular proliferation, differentiation, and growth. Previous studies showed that single-nucleotide polymorphisms (SNPs) of IGF-1 are associated with various diseases. This case-control study aimed to examine the relationship between IGF-1 polymorphisms and IgA nephropathy (IgAN) risk in a Chinese Han population. METHODS: We recruited...

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Identifiers

PMID: 29402846
DOI: 10.1159/000486914

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