Article
Haptoglobin Genotype Is a Determinant of Hemoglobin Adducts and Vitamin E Content in HDL.
Journal of diabetes research - 1 Jan 2018
Goldenstein Hagit, Levy Nina S, Ward John, Costacou Tina, Levy Andrew P
Abstract excerpt
Haptoglobin (Hp) is an abundant hemoglobin- (Hb-) binding serum protein and a constituent of the HDL proteome. In man, there exists a common polymorphism at the Hp locus with two common alleles defined by the presence (Hp 2 allele) or absence (Hp 1 allele) of a 1.7 kb in-frame partial duplication of exons 3 and 4 of the Hp gene. Numerous studies have demonstrated that the Hp 2-2 genotype is associated with a...
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