Article
An enzyme linked immunosorbent assay (ELISA) for the determination of the human haptoglobin phenotype.
Clinical chemistry and laboratory medicine - 1 Aug 2013
Levy Nina S, Vardi Moshe, Blum Shany, Miller-Lotan Rachel, Afinbinder Yefim, Cleary Patricia A, Paterson Andrew D, Bharaj Bhupinder, Snell-Bergeon Janet K, Rewers Marian J, Lache Orit, Levy Andrew P
Abstract excerpt
BACKGROUND: Haptoglobin (Hp) is an abundant serum protein which binds extracorpuscular hemoglobin (Hb). Two alleles exist in humans for the Hp gene, denoted 1 and 2. Diabetic individuals with the Hp 2-2 genotype are at increased risk of developing vascular complications including heart attack, stroke, and kidney disease. Recent evidence shows that treatment with vitamin E can reduce the risk of diabetic vascular...
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