Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Microglia/macrophage polarization dynamics reveal novel mechanism of injury expansion after focal cerebral ischemia.

Stroke - 1 Nov 2012

Hu Xiaoming, Li Peiying, Guo Yanling, Wang Haiying, Leak Rehana K, Chen Songela, Gao Yanqin, Chen Jun

Abstract excerpt

BACKGROUND AND PURPOSE: Mononuclear phagocytes are highly plastic cells that assume diverse phenotypes in response to microenvironmental signals. The phenotype-specific roles of microglia/macrophages in ischemic brain injury are poorly understood. A comprehensive characterization of microglia/macrophage polarization after ischemia may advance our knowledge of poststroke damage/recovery. METHODS: Focal transient...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain Ischemia
Share to Cell Communication

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Polarity

Share to Coculture Techniques

Share to Galectin 3

Share to Macrophage-1 Antigen

Share to Macrophage Activation

Share to Microglia

Source

Identifiers

PMID: 22933588
DOI: 10.1161/STROKEAHA.112.659656

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Microglia/macrophage polarization dynamics reveal novel mechanism of injury expansion after focal cerebral ischemia.PMID 22933588Read ↗

Selective modulation of microglia polarization to M2 phenotype for stroke treatment.Semantic proximity Read ↗

Microglia and Monocytes/Macrophages Polarization Reveal Novel Therapeutic Mechanism against Stroke.Semantic proximity Read ↗

Microglial and macrophage polarization—new prospects for brain repair.Semantic proximity Read ↗

Treatment targets for M2 microglia polarization in ischemic stroke.Semantic proximity Read ↗

Microglia/macrophage polarization: Fantasy or evidence of functional diversity?Semantic proximity Read ↗

Microglial immunosurveillance after ischemic stroke: dynamic phenotypes, neurovascular interactions, and therapeutic opportunities.Semantic proximity Read ↗

Phagocytosis converts infiltrated monocytes to microglia-like phenotype in experimental brain ischemia.Semantic proximity Read ↗

Temporal pattern of expression and colocalization of microglia/macrophage phenotype markers following brain ischemic injury in mice.Semantic proximity Read ↗

A potential gliovascular mechanism for microglial activation: differential phenotypic switching of microglia by endothelium versus astrocytes.Semantic proximity Read ↗

Modulating the polarization phenotype of microglia - A valuable strategy for central nervous system diseases.Semantic proximity Read ↗

Research Progress on Treating Spinal Cord Injury by Modulating the Phenotype of Microglia.Semantic proximity Read ↗

Managing inflammation after spinal cord injury through manipulation of macrophage function.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.