Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Paired genomic profiling of primary tumor and lymph-node metastases identifies candidate prognostic features in penile squamous cell carcinoma.

The oncologist - 6 Aug 2026

Lou Kexin, Liang Linghui, Cai Hongzhou, Xu Ting, Wang Fufeng, Wang Di, Jing Qifan, Yin Jiani C, Zhang Xiaoxiang, Xu Zicheng

Abstract excerpt

BACKGROUND: Penile squamous cell carcinoma (PSCC) is a rare malignancy with limited genomic data in Asian populations. Lymph node metastasis heavily dictates prognosis, yet molecular determinants of progression remain poorly understood. We aimed to characterize the genomic landscape and explore candidate prognostic genomic features using paired primary and metastatic PSCC tumors. PATIENTS AND METHODS: Targeted...

Read the complete abstract on PubMed

Topics

Humans
Male
Penile Neoplasms
Carcinoma, Squamous Cell
Lymphatic Metastasis
Prognosis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Middle Aged

Biomarkers, Tumor

Aged

Mutation

Genomics

Source

Open in PubMed Open full text

Identifiers

PMID: 42658002
DOI: 10.1093/oncolo/oyag319
PMCID: PMC13537821

Genes

CCND1
FGF19
TERT
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 20 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Paired genomic profiling of primary tumor and lymph-node metastases identifies candidate prognostic features in penile squamous cell carcinoma.PMID 42658002Read ↗

Whole-exome Sequencing in Penile Squamous Cell Carcinoma Uncovers Novel Prognostic Categorization and Drug Targets Similar to Head and Neck Squamous Cell Carcinoma.Semantic proximity Read ↗

Pathogenesis of Penile Squamous Cell Carcinoma: Molecular Update and Systematic Review.Semantic proximity Read ↗

Molecular characterization and integrative genomic analysis of a panel of newly established penile cancer cell lines.Semantic proximity Read ↗

Whole genome analysis reveals the genomic complexity in metastatic cutaneous squamous cell carcinomaSemantic proximity Read ↗

Molecular characterization of metastatic penile squamous cell carcinoma in developing countries and its impact on clinical outcomes: LACOG 2018 translational study.Semantic proximity Read ↗

Genomic Profiles and Clinical Outcomes of Penile Squamous Cell Carcinoma With Elevated Tumor Mutational BurdenSemantic proximity Read ↗

Whole genome analysis reveals the genomic complexity in metastatic cutaneous squamous cell carcinomaSemantic proximity Read ↗

Understanding genomics and the immune environment of penile cancer to improve therapy.Semantic proximity Read ↗

Comparative genomic landscape of primary and metastatic bladder urothelial carcinoma in a large-scale cohort.Semantic proximity Read ↗

Targeted next-generation sequencing of matched localized and metastatic primary high-risk SCCs identifies driver and co-occurring mutations and novel therapeutic targets.Semantic proximity Read ↗

Genomic analysis of metastatic cutaneous squamous cell carcinoma.Semantic proximity Read ↗

Mutational landscape of penile squamous cell carcinoma in a Chinese populationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.