Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Chimeric Humanized Mouse Model by Engrafting the Human Induced Pluripotent Stem Cell-Derived Hepatocyte-Like Cell for the Chronic Hepatitis B Virus Infection

8 May 2018

Abstract excerpt

Humanized mouse model generated by grafting primary human hepatocytes (PHHs) to immunodeficient mouse has contributed invaluably to understanding the pathogenesis of hepatitis B virus (HBV). However, the source of PHHs is limited, which necessitates the search for alternatives. Recently, hepatocyte-like cells (HLCs) generated from human induced pluripotent stem cells (hiPSCs) have been used for in vitro HBV...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hepatitis B Virus Studies
Share to Liver Disease Diagnosis and Treatment
Share to Liver physiology and pathology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29867819
DOI: 10.3389/fmicb.2018.00908

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Chimeric Humanized Mouse Model by Engrafting the Human Induced Pluripotent Stem Cell-Derived Hepatocyte-Like Cell for the Chronic Hepatitis B Virus InfectionPMID 29867819Read ↗

Human liver chimeric mice provide a model for hepatitis B and C virus infection and treatmentSemantic proximity Read ↗

New horizons for studying human hepatotropic infectionsSemantic proximity Read ↗

The Application of Induced Pluripotent Stem Cells Against Liver Diseases: An Update and a ReviewSemantic proximity Read ↗

Use of human hepatocyte-like cells derived from induced pluripotent stem cells as a model for hepatocytes in hepatitis C virus infectionSemantic proximity Read ↗

Are Humanized Mouse Models Useful for Basic Research of Hepatocarcinogenesis through Chronic Hepatitis B Virus Infection?Semantic proximity Read ↗

Modeling hepatitis C virus infection using human induced pluripotent stem cellsSemantic proximity Read ↗

Recapitulation of hepatitis B virus–host interactions in liver organoids from human induced pluripotent stem cellsSemantic proximity Read ↗

Human induced pluripotent stem cells derived hepatocytes: rising promise for disease modeling, drug development and cell therapySemantic proximity Read ↗

Agonist c-Met Monoclonal Antibody Augments the Proliferation of hiPSC-derived Hepatocyte-Like Cells and Improves Cell Transplantation Therapy for Liver Failure in MiceSemantic proximity Read ↗

Mice with Liver Composed of Human Hepatocytes as an Animal Model for Drug TestingSemantic proximity Read ↗

Persistent hepatitis B virus and HIV coinfections in dually humanized mice engrafted with human liver and immune systemSemantic proximity Read ↗

Human induced-pluripotent stem cell-derived hepatocyte-like cells as an in vitro model of human hepatitis B virus infectionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.