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Modeling hepatitis C virus infection using human induced pluripotent stem cells

30 Jan 2012

Abstract excerpt

Human pathogens impact patient health through a complex interplay with the host, but models to study the role of host genetics in this process are limited. Human induced pluripotent stem cells (iPSCs) offer the ability to produce host-specific differentiated cells and thus have the potential to transform the study of infectious disease; however, no iPSC models of infectious disease have been described. Here we...

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PMID: 22308485
DOI: 10.1073/pnas.1121400109

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