Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Recapitulation of hepatitis B virus–host interactions in liver organoids from human induced pluripotent stem cells

16 Aug 2018

Abstract excerpt

Therapies against hepatitis B virus (HBV) have improved in recent decades; however, the development of individualized treatments has been limited by the lack of individualized infection models. In this study, we used human induced pluripotent stem cell (hiPSC) to generate a functional liver organoid (LO) that inherited the genetic background of the donor, and evaluated its application in modeling HBV infection...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hepatitis B Virus Studies
Share to Liver physiology and pathology
Share to Organ Transplantation Techniques and Outcomes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30120080
DOI: 10.1016/j.ebiom.2018.08.014

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Recapitulation of hepatitis B virus–host interactions in liver organoids from human induced pluripotent stem cellsPMID 30120080Read ↗

Modeling human liver organ development and diseases with pluripotent stem cell-derived organoidsSemantic proximity Read ↗

Next-Generation Liver Medicine Using Organoid ModelsSemantic proximity Read ↗

Production of Human Pluripotent Stem Cell-Derived Hepatic Cell Lineages and Liver Organoids: Current Status and Potential ApplicationsSemantic proximity Read ↗

Using Liver Organoids as Models to Study the Pathobiology of Rare Liver DiseasesSemantic proximity Read ↗

Liver Organoids: Updates on Disease Modeling and Biomedical ApplicationsSemantic proximity Read ↗

Engineered Platforms for Maturing Pluripotent Stem Cell–Derived Liver Cells for Disease ModelingSemantic proximity Read ↗

Liver organoids: established tools for disease modeling and drug developmentSemantic proximity Read ↗

Pluripotent Stem Cell-Derived Hepatocyte-like Cells: Induction Methods and ApplicationsSemantic proximity Read ↗

Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systemsSemantic proximity Read ↗

The Application of Induced Pluripotent Stem Cells Against Liver Diseases: An Update and a ReviewSemantic proximity Read ↗

Human Induced Pluripotent Stem Cells in HepatologySemantic proximity Read ↗

The Use of Induced Pluripotent Stem Cells for the Study and Treatment of Liver DiseasesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.