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Article

Association of Toll-like receptor 3 and Toll-like receptor 9 single-nucleotide polymorphisms with hepatitis C virus persistence among Egyptians.

Archives of virology - 1 Sept 2018

Hamdy Shaimaa, Osman Ahmed M, Zakaria Zainab A, Galal Iman, Sobhy Maha, Hashem Mohamed, Allam Walaa R, Abdel-Samiee Mohamed, Rewisha Eman, Waked Imam, Abdelwahab Sayed F

Abstract excerpt

Toll-like receptors (TLRs) give the innate immune system a considerable specificity for a large range of pathogens. TLR3 detects dsRNA of viruses while TLR9 recognizes bacterial and viral unmethylated CpG motifs. This study examined whether there is a potential association between single-nucleotide polymorphisms (SNPs) in the TLR3.rs3775290 (c.1377C/T), TLR9.rs5743836 (-1237T→C) and TLR9.rs352140 (G2848A) genes...

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Share to Egypt
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Share to Immunity, Innate
Share to Lymphocytes
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Share to Remission, Spontaneous
Share to Toll-Like Receptor 3
Share to Toll-Like Receptor 9

Source

Identifiers

PMID: 29860675
DOI: 10.1007/s00705-018-3893-8

Genes

TLR9
TLR3

Variants

rs352140

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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