Article
Association of the polymorphism of the Toll-like receptor (TLR)-3 and TLR-9 genes with hepatitis C virus-specific cell-mediated immunity outcomes among Egyptian health-care workers.
Clinical and experimental immunology - 1 Jan 2021
Abdelwahab S F, Hamdy S, Osman A M, Zakaria Z A, Galal I, Sobhy M, Hashem M, Allam W R, Abdel-Samiee M, Rewisha E, Waked I
Abstract excerpt
Variations in the immune response could explain resistance to hepatitis C virus (HCV) infection. Toll-like receptor gene (TLR)-3 is an innate detector of dsRNA viruses, and the TLR-9 gene recognizes bacterial and viral unmethylated cytosine-phosphate-guanosine (CpG) motifs. We previously reported that the TLR-3.rs3775290 CC genotype was associated with HCV chronicity and that the TLR-9 gene played no major role...
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