Activity of Genes with Functions in Human Williams–Beuren Syndrome Is Impacted by Mobile Element Insertions in the Gray Wolf Genome

Abstract excerpt

In canines, transposon dynamics have been associated with a hyper-social behavioral syndrome, although the functional mechanism has yet to be described. We investigate the epigenetic and transcriptional consequences of these behavior-associated mobile element insertions (MEIs) in dogs and Yellowstone gray wolves. We posit that the transposons themselves may not be the causative feature; rather, their...

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