Article

Contribution of Retrotransposition to Developmental Disorders

2018-11-16

Abstract excerpt

Mobile genetic Elements (MEs) are segments of DNA which, through an RNA intermediate, can generate new copies of themselves and other transcribed sequences through the process of retrotransposition (RT). In humans several disorders have been attributed to RT, but the role of RT in severe developmental disorders (DD) has not yet been explored. As such, we have identified RT-derived events in 9,738 exome sequenced t...

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Literature Corpus work: 5e0c4dc7-7af2-552e-b3cc-06588654e182
DOI: 10.1101/471375

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