Article
The investigation of host genetic variants of toll-like receptor 7 and 8 in COVID-19.
Nucleosides, nucleotides & nucleic acids - 1 Jan 2023
Bagci Gokhan, Gundogdu Oguz, Pektas Ayse Nur, Bagci Binnur, Avci Onur, Gursoy Sinan, Kaygusuz Kenan, Elaldi Nazif
Abstract excerpt
Toll-like receptors (TLRs) recognize infectious agents and play an important role in the innate immune system. Studies have suggested that TLR single nucleotide polymorphisms (SNPs) are associated with poor antiviral responses against SARS-CoV-2. Therefore, we aimed to investigate the relationship of TLR7 and TLR8 (SNPs) with COVID-19 disease prognosis. A total of 120 COVID-19 patients, 40 outpatients, 40...
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