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Article

Robust and sensitive subtype-generic HIV-1 pol genotyping for use with dried serum spots in epidemiological studies.

Journal of virological methods - 1 Sept 2018

Hauser Andrea, Meixenberger Karolin, Machnowska Patrycja, Fiedler Stefan, Hanke Kirsten, Hofmann Alexandra, Bartmeyer Barbara, Bremer Viviane, Bannert Norbert, Kuecherer Claudia

Abstract excerpt

HIV-1 genotyping of larger pol-fragments from dried serum/plasma spots (DSS/DPS) is often hindered by RNA-degradation during transportation at ambient temperature. We evaluated an in-house HIV-1 DSS/DPS-genotyping assay designed in two shorter overlapping fragments covering all resistance mutations in protease and reverse transcriptase. Validation criteria such as specificity, detection limit, accuracy,...

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Identifiers

PMID: 29859195
DOI: 10.1016/j.jviromet.2018.05.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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