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“Exceptional brain aging” without Alzheimer’s disease: triggers, accelerators, and the net sum game

1 Jun 2018

Abstract excerpt

BACKGROUND: As human longevity increases and Alzheimer's disease (AD) increasingly becomes a significant societal burden, finding pathways or protective factors that facilitate exceptional brain aging without AD pathophysiologies (ADP) will be critical. The goal of this viewpoint is two-fold: 1) to present evidence for "exceptional brain aging" without ADP; and 2) to bring together ideas and observations from the...

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PMID: 29859131
DOI: 10.1186/s13195-018-0373-z

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