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Article

Genome-Wide Analysis of Dental Caries Variability Reveals Genotype-by-Environment Interactions.

Genes - 17 Mar 2023

Zou Tianyu, Foxman Betsy, McNeil Daniel W, Weinberg Seth M, Marazita Mary L, Shaffer John R

Abstract excerpt

Genotype-by-environment interactions (GEI) may influence dental caries, although their effects are difficult to detect. Variance quantitative trait loci (vQTL) may serve as an indicator of underlying GEI effects. The aim of this study was to investigate GEI effects on dental caries by prioritizing variants from genome-wide vQTL analysis. First, we identified vQTLs from ~4.3 M genome-wide variants in three cohorts...

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Identifiers

PMID: 36981009
DOI: 10.3390/genes14030736
PMCID: PMC10048401

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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