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Article

GSTP1 rs4147581 C>G and NLRP3 rs3806265 T>C as Risk Factors for Chronic Obstructive Pulmonary Disease: A Case-Control Study.

International journal of chronic obstructive pulmonary disease - 1 Jan 2024

Li Honge, Wang Raorao, Wei Xueyan, Zhang Chunyan, Pei Wenhui, Zhang Xuhui, Yang Zhen, Li Zhi, Zhang Yuhuan, Shi Yanli, Wang Yunchao, Wang Xinhua

Abstract excerpt

Background: Chronic obstructive pulmonary disease (COPD) is a chronic respiratory ailment influenced by a blend of genetic and environmental factors. Inflammatory response and an imbalance in oxidative-antioxidant mechanisms constitute the primary pathogenesis of COPD. Glutathione S-transferase P1(GSTP1) plays a pivotal role as an antioxidant enzyme in regulating oxidative-antioxidant responses in the pulmonary...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Glutathione S-Transferase pi

Share to NLR Family, Pyrin Domain-Containing 3 Protein

Share to Polymorphism, Single Nucleotide

Share to Pulmonary Disease, Chronic Obstructive

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Source

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Identifiers

PMID: 38410140
DOI: 10.2147/COPD.S445680
PMCID: PMC10896110

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