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Article

Comparative genomics and functional study of lipid metabolic genes in Caenorhabditis elegans.

BMC genomics - 12 Mar 2013

Zhang Yuru, Zou Xiaoju, Ding Yihong, Wang Haizhen, Wu Xiaoyun, Liang Bin

Abstract excerpt

BACKGROUND: Animal models are indispensable to understand the lipid metabolism and lipid metabolic diseases. Over the last decade, the nematode Caenorhabditis elegans has become a popular animal model for exploring the regulation of lipid metabolism, obesity, and obese-related diseases. However, the genomic and functional conservation of lipid metabolism from C. elegans to humans remains unknown. In the present...

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PMID: 23496871
DOI: 10.1186/1471-2164-14-164
PMCID: PMC3602672

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