Article
Association between single nucleotide polymorphisms IL17RA rs4819554 and IL17E rs79877597 and Psoriasis in a Spanish cohort.
Journal of dermatological science - 1 Nov 2015
Batalla Ana, Coto Eliecer, González-Lara Leire, González-Fernández Daniel, Gómez Juan, Aranguren Tamara F, Queiro Rubén, Santos-Juanes Jorge, López-Larrea Carlos, Coto-Segura Pablo
Abstract excerpt
BACKGROUND: The IL17 pathway plays an important role in the pathogenesis of psoriasis (PsO). OBJECTIVES: To determine whether the variation at the IL17 pathway genes was linked to the risk for PsO or had an effect on disease severity and the risk for Psoriatic arthritis (PsA). METHODS: Cross-sectional observational study of 580 psoriasis patients and 567 healthy controls who were genotyped for six single...
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