Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Endplate Defect Is Heritable, Associated With Low Back Pain and Triggers Intervertebral Disc Degeneration: A Longitudinal Study From TwinsUK.

Spine - 1 Nov 2018

Munir Sabrina, Freidin Maxim B, Rade Marinko, Määttä Juhani, Livshits Gregory, Williams Frances M K

Abstract excerpt

STUDY DESIGN: Longitudinal study of spine magnetic resonance imaging (MRI) in a large-scale population-based study. OBJECTIVE: To determine the order of appearance of degenerative change in vertebral bodies and intervertebral discs. We also sought to define the influence of endplate defect on low back pain (LBP) and to determine whether there is a genetic influence on endplate defect. SUMMARY OF BACKGROUND DATA:...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cartilage
Share to Congenital Abnormalities

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Intervertebral Disc Degeneration

Share to Longitudinal Studies

Share to Low Back Pain

Share to Lumbar Vertebrae

Share to Magnetic Resonance Imaging

Share to Young Adult

Source

Identifiers

PMID: 29847371
DOI: 10.1097/BRS.0000000000002721

Genes

LBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Endplate Defect Is Heritable, Associated With Low Back Pain and Triggers Intervertebral Disc Degeneration: A Longitudinal Study From TwinsUK.PMID 29847371Read ↗

Two subtypes of intervertebral disc degeneration distinguished by large-scale population-based study.Semantic proximity Read ↗

Vertebral endplate change as a feature of intervertebral disc degeneration: a heritability study.Semantic proximity Read ↗

Intervertebral disc degeneration: evidence for two distinct phenotypes.Semantic proximity Read ↗

Structural vertebral endplate nomenclature and etiology: a study by the ISSLS Spinal Phenotype Focus Group.Semantic proximity Read ↗

Phenotype profiling of Modic changes of the lumbar spine and its association with other MRI phenotypes: a large-scale population-based study.Semantic proximity Read ↗

[Long-lasting low back pain and MRI changes in the intervertebral discs].Semantic proximity Read ↗

The association of lumbar intervertebral disc degeneration with low back pain is modified by underlying genetic propensity to pain.Semantic proximity Read ↗

Protocol for disease-oriented Russian disc degeneration study (RuDDS) biobank facilitating functional omics studies of lumbar disc degenerationSemantic proximity Read ↗

Genetic influences on cervical and lumbar disc degeneration: a magnetic resonance imaging study in twins.Semantic proximity Read ↗

Progression of lumbar disc degeneration over a decade: a heritability study.Semantic proximity Read ↗

Association of vitamin D receptor gene polymorphisms with disc degeneration.Semantic proximity Read ↗

Lumbar disc degeneration: epidemiology and genetic influences.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.