Article
Association of TNF-α-308 Polymorphism with Susceptibility to Autoimmune Hepatitis in Tunisians.
Biochemical genetics - 1 Dec 2018
Chaouali Marwa, Azaiez Mouna Ben, Tezeghdenti Aymen, Lagha Awatef, Yacoubi-Oueslati Basma, Ghazouani Ezzeddine, Abdallah Hatem Ben, Kochkar Radhia
Abstract excerpt
Autoimmune hepatitis (AIH) is a chronic hepatitis of unknown etiology and several proinflammatory cytokines are implicated in its pathogenesis. The association of TNF-α gene polymorphism with AIH onset is not fully elucidated especially in the Tunisian population. The aim of this study was to determine the association of TNF-α (-308 G > A) polymorphism with AIH susceptibility and with TNF-α expression or clinical...
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