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Article

Association of TNF-Alpha gene polymorphisms and susceptibility to hepatitis B virus infection in Egyptians.

Human immunology - 1 Nov 2017

Talaat Roba M, Abdelkhalek Mohamed S, El-Maadawy Eman A, Abdel-Mageed Wael S, El-Shenawy Soha Z, Osman Mohamed A

Abstract excerpt

Tumor necrosis factor alpha (TNF-α) is one of the important cytokine in generating an immune response against hepatitis B virus (HBV). Genetic polymorphisms might influence gene transcription, leading to disturbance in cytokine production. We hypothesized that single nucleotide polymorphism (SNPs) in TNF-α gene could affect the pathogenesis of HBV. To test this hypothesis, we investigated the role of TNF-α...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29054398
DOI: 10.1016/j.humimm.2017.10.006

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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