Article
Mechanisms of Crystalloid versus Colloid Osmosis across the Peritoneal Membrane.
Journal of the American Society of Nephrology : JASN - 1 Jul 2018
Morelle Johann, Sow Amadou, Fustin Charles-André, Fillée Catherine, Garcia-Lopez Elvia, Lindholm Bengt, Goffin Eric, Vandemaele Fréderic, Rippe Bengt, Öberg Carl M, Devuyst Olivier
Abstract excerpt
Background Osmosis drives transcapillary ultrafiltration and water removal in patients treated with peritoneal dialysis. Crystalloid osmosis, typically induced by glucose, relies on dialysate tonicity and occurs through endothelial aquaporin-1 water channels and interendothelial clefts. In contrast, the mechanisms mediating water flow driven by colloidal agents, such as icodextrin, and combinations of osmotic...
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