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Article

Differential effects of biocompatible peritoneal dialysis fluids on human mesothelial and endothelial cells in 2D and 3D phenotypes.

Artificial organs - 1 May 2024

Jagirdar Rajesh M, Pitaraki Eleanna, Rouka Erasmia, Papazoglou Eleftherios D, Bartosova Maria, Zebekakis Pantelis, Schmitt Claus Peter, Zarogiannis Sotirios G, Liakopoulos Vassilios

Abstract excerpt

INTRODUCTION: Peritoneal dialysis (PD) is a life maintaining treatment in patients with end-stage renal disease. Its chronic application leads to peritoneal mesothelial layer denudation and fibrotic transformation along with vascular activation of inflammatory pathways. The impact of different PD fluids (PDF) on mesothelial and endothelial cell function and repair mechanisms are not comprehensively described....

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PMID: 38151979
DOI: 10.1111/aor.14703

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