Article

Trans-epithelial Fluid Pumping Performance of Renal Epithelial Cells and Mechanics of Cystic Expansion

2021-05-28

Abstract excerpt

<title>Abstract</title> <p>Using a novel microfluidic platform to recapitulate fluid transport activity of kidney cells, we report that renal epithelial cells can actively generate hydraulic pressure gradients across the epithelium. The fluidic flux declines with increasing hydraulic pressure until a stall pressure, at which the flux vanishes--in a manner similar to mechanical fluidic pumps. The developed pressur...

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Literature Corpus work: d6f4380f-cad6-5cdd-956f-2abf73ec84b8
DOI: 10.21203/rs.3.rs-524708/v1

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