Article
Mapping depression rating scale phenotypes onto research domain criteria (RDoC) to inform biological research in mood disorders.
Journal of affective disorders - 1 Oct 2018
Ahmed Ahmed T, Frye Mark A, Rush A John, Biernacka Joanna M, Craighead W Edward, McDonald William M, Bobo William V, Riva-Posse Patricio, Tye Susannah J, Mayberg Helen S, Hall-Flavin Daniel K, Skime Michelle K, Jenkins Greg D, Wang Liewei, Krishnan Ranga Rama, Weinshilboum Richard M, Kaddurah-Daouk Rima, Dunlop Boadie W
Abstract excerpt
BACKGROUND: Substantial research progress can be achieved if available clinical datasets can be mapped to the National Institute of Mental Health Research-Domain-Criteria (RDoC) constructs. This mapping would allow investigators to both explore more narrowly defined clinical phenotypes and the relationship of these phenotypes to biological markers and clinical outcomes approximating RDoC criteria. METHODS: Using...
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