Association between a common missense variant in LOXL3 gene and the risk of non-syndromic cleft palate.

doi:10.1111/cga.12288

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Article

Association between a common missense variant in LOXL3 gene and the risk of non-syndromic cleft palate.

Congenital anomalies - 1 Jul 2018

Khan Mohammad Faisal J, Little Julian, Mossey Peter A, Steegers-Theunissen Régine P M, Bonsi Martina, Bassi Andreasi Rita, Rubini Michele

Abstract excerpt

To investigate possible association between functional common variants in the lysyl oxidase like 3 gene and non-syndromic cleft palate we selected a common missense variant p.Ile615Phe (rs17010021), which was predicted to have a probably damaging effect on the lysyl oxidase like 3 enzyme. We genotyped 258 non-syndromic cleft palate case-parent triads of European origin and tested genetic association using the...

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Identifiers

PMID: 29802726
DOI: 10.1111/cga.12288

Genes

LOXL3

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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